Partner thrombophilia risk

Your partner has an increased risk of thrombophilia; this increases the risk of fetal thrombophilia. Here is what you need to know.

Based on your partner’s history information, he has an increased risk of genetic thrombophilia that may be inherited by the fetus and cause fetal loss and other pregnancy-related complications.

Thrombophilia is a condition that makes the patients who suffer from it have an increased tendency to clot within their own blood vessels.  Normally the blood flows throughout the vascular system without clotting.  When a vessel is broken down (injury) and bleeding commences, the clotting mechanism of a normal person is forming a plug, to stop the bleeding. This plug is the result of a very complex coagulation mechanism, which requires significant coordination of many different proteins, antibodies, and other chemicals produced within the human tissues.

Women who do not have thrombophilia experience recurrent pregnancy loss and infertility issues if the partner has genetic thrombophilia that he is passing to the fetus. Half of all pregnancy failures are caused by undiagnosed paternal and fetal thrombophilia. Fetal thrombophilia can cause all the pregnancy complications listed below:

  1. Failure of the embryo to attach to the uterine lining (implantation failure).
  2. Recurrent miscarriages
  3. Growth failure of the fetus because of insufficient placenta growth.
  4. Hypertensive disorders of the pregnancy (Preeclampsia/Toxemia).
  5. Decreased amniotic fluid volume (Oligohydramnios).
  6. Partial or complete separation of the placenta (Abruptio placentae).
  7. Silent premature cervical changes may lead to premature birth.
  8. Pre-term labor and delivery.
  9. “Unexplained” intrauterine fetal demise (death).
  10. Severe fetal deprivation of oxygen may lead to variable degrees of mental problems including cerebral palsy.
  11. Finally, clots may form within the maternal veins and that can lead to thrombophlebitis or deep vein thrombosis, which can be dangerous for the mother.  However, this last one is less frequent, and it is more likely to happen in patients with specific coagulation problems. However, nine out of ten times, we are concerned with the effects that thrombophilia has on the development of the placenta and the baby, and the treatments we employ concern the protection of the placenta.

What you need to do:

Speak to your PCP or OB doctor and ask them to test your partner for genetic thrombophilia. This knowledge will help your doctor to figure out the risk of the fetus having genetic thrombophilia and thus design a customized treatment protocol. If your primary doctor is not familiar with this knowledge, you are welcome to visit Dr. Kofinas to complete your workup and get a customized protocol for your next pregnancy.